PK in Pregnancy Initiative: MHRA & Bill and Melinda Gates Foundation

Over two-thirds of women receive prescription drugs while pregnant.  These may be for pre-existing medical conditions or symptoms arising as a result of pregnancy.  Most often, the advice is to avoid the use of medicines during pregnancy and breastfeeding. Changes in maternal physiology as a result of pregnancy may affect the disposition of any administered […]

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Biology in Numbers

In humans the average duration of a single eye blink is 0.1 second, additionally the time between blinks is generally around 2.8 seconds.  It also takes one photon of light to excite a rod in the retina of the eye.  Why list this information?  Well it illustrates some of the many processes and functions that […]

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Pharmacogenetics in the High Street

During development of a new drug molecule, a wealth of information is collected about the new medicine, some of this will end up on the drug label.  It has been estimated that up to 40% of the drug label consists of data of a clinical pharmacology nature; often this may include pharmacogenomic (Pgx) information.  Pgx […]

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